Brazilian bioethics became consolidated in the 1990s. It was during
this time that teaching and research centers were instituted,
associative groups were created, and the first papers of Brazilian
authors were published. In Brazil, the first years of teaching and
research in bioethics were marked by a strong influence of the United
States, particularly in the theoretic and thematic fields. Among the
main topics of discussion were subjects related to the end of life and
to research involving human beings, and bioethics was then chiefly
influenced by Tom Beauchamp and James Childress's theory of the
four principles.